| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 5/14/24 5:00 PM | Club Atlético Peñarol | Club Atletico Mineiro | Group G | 2-0 |
| 5/14/24 5:00 PM | LDU Quito | Junior FC | Group D | 0-1 |
| 5/14/24 5:00 PM | CA Talleres | Cobresal | Group B | 1-0 |
| 5/14/24 7:30 PM | River Plate | Club Libertad | Group H | 2-0 |
| 5/14/24 9:00 PM | Millonarios FC | Palestino | Group E | 1-1 |
| 5/15/24 5:00 PM | Deportivo Tachira | Club Nacional de Football | Group H | 0-1 |
| 5/15/24 5:00 PM | The Strongest | Huachipato | Group C | 4-0 |
| 5/15/24 7:00 PM | Alianza Lima | Colo-Colo | Group A | 1-1 |
| 5/15/24 7:30 PM | Palmeiras | Independiente del Valle | Group F | 2-1 |
| 5/15/24 7:30 PM | Flamengo | Club Bolívar | Group E | 4-0 |
| 5/16/24 5:00 PM | Rosario Central | Caracas FC | Group G | 4-1 |
| 5/16/24 5:00 PM | Universitario | Botafogo | Group D | 0-1 |
| 5/16/24 5:00 PM | Fluminense | Club Cerro Porteno | Group A | 2-1 |
| 5/16/24 7:00 PM | CA San Lorenzo | Liverpool F.C. | Group F | 3-2 |
| 5/16/24 7:00 PM | FC Sao Paulo | Barcelona SC | Group B | 0-0 |
| 6/8/24 5:00 PM | Gremio Porto Alegre | Estudiantes de La Plata | Group C | --- |